Sex biases in the mutation rate.

doi:10.1016/s0168-9525(98)01577-7

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Article

Sex biases in the mutation rate.

Trends in genetics : TIG - 1 Nov 1998

Hurst L D, Ellegren H

Abstract excerpt

Men have more germ-line cell divisions than women. Does this lead to a higher mutation rate in males? Most estimates of the proportion of mutations originating in men come either from direct observation of disease-inducing mutations or from analysis of the relative rate of evolution of sex-linked...

Topics

Aging
Animals
Cell Division
DNA Methylation
Evolution, Molecular
Female
Genes, Dominant
Germ Cells
Humans
Male
Models, Genetic
Mutation
Sex Factors

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