Article
Male-driven evolution of DNA sequences.
Nature - 22 Apr 1993
Shimmin L C, Chang B H, Li W H
Abstract excerpt
It is commonly believed that the mutation rate is much higher in the human male germ line than in the female germ line because the number of germ-cell divisions per generation is much larger in males than in females. But direct estimation of mutation rates is difficult, relying mainly on sex-linked genetic diseases, so the ratio (alpha m) of male to female mutation rates is not clear. It has been noted that if...
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