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How important is DNA replication for mutagenesis?

Molecular biology and evolution - 1 Jun 2000

Huttley G A, Jakobsen I B, Wilson S R, Easteal S

Abstract excerpt

Rates of mutation and substitution in mammals are generally greater in the germ lines of males. This is usually explained as resulting from the larger number of germ cell divisions during spermatogenesis compared with oogenesis, with the assumption made that mutations occur primarily during DNA replication. However, the rate of cell division is not the only difference between male and female germ lines, and...

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PMID: 10833199
DOI: 10.1093/oxfordjournals.molbev.a026373

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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