Article
Oxidative polymorphism of debrisoquine is not related to the risk of Alzheimer's disease.
Journal of the neurological sciences - 1 Jul 1993
Benítez J, Barquero M S, Coria F, Molina J A, Jiménez-Jiménez F J, Ladero J M
Abstract excerpt
Oxidative polymorphism of debrisoquine has been studied in patients suffering from many spontaneous disorders which show genetic and/or environmental factors in their pathogenesis. To elucidate whether any relationship exists between this genetic polymorphism and the risk of developing Alzheimer disease (AD) we determined the oxidative phenotype and metabolic ratio (MR) of debrisoquine (DBQ) in 47 patients with...
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