Article
Oxidative polymorphism of debrisoquine is not related to the risk of Alzheimer's disease.
Journal of the neurological sciences - 1 Jul 1993
Benítez J, Barquero M S, Coria F, Molina J A, Jiménez-Jiménez F J, Ladero J M
Abstract excerpt
Oxidative polymorphism of debrisoquine has been studied in patients suffering from many spontaneous disorders which show genetic and/or environmental factors in their pathogenesis. To elucidate whether any relationship exists between this genetic polymorphism and the risk of developing Alzheimer...
Topics
- Aged
- Alzheimer Disease
- Cytochrome P-450 CYP2D6
- Cytochrome P-450 Enzyme System
- Debrisoquin
- Female
- Genetic Predisposition to Disease
- Humans
- Inactivation, Metabolic
- Male
- Middle Aged
- Mixed Function Oxygenases
- Oxidation-Reduction
- Phenotype
- Polymorphism, Genetic
- Risk Factors
