Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Nucleotide sequence encoding the carboxyl-terminal half of apolipoprotein B from spontaneously hypercholesterolemic pigs.

Journal of lipid research - 1 Aug 1993

Purtell C, Maeda N, Ebert D L, Kaiser M, Lund-Katz S, Sturley S L, Kodoyianni V, Grunwald K, Nevin D N, Aiello R J

Abstract excerpt

Previous studies from this laboratory characterized the hypercholesterolemia of pigs with a mutant allele of apolipoprotein B (apoB), designated Lpb5. This apoB allele is associated with low density lipoprotein (LDL) particles deficient in binding to the LDL receptor. To identify potential causative mutations in Lpb5 DNA, 10.6 kb of genomic DNA, encoding the carboxyl-terminal 58% of apoB were sequenced from the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Amino Acid Sequence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Base Sequence

Share to Molecular Sequence Data

Share to Mutation

Share to Polymerase Chain Reaction

Share to Sequence Analysis, DNA

Source

Identifiers

PMID: 8409766

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Nucleotide sequence encoding the carboxyl-terminal half of apolipoprotein B from spontaneously hypercholesterolemic pigs.PMID 8409766Read ↗

Determination of pig apolipoprotein B genotype by gene amplification and restriction fragment length polymorphism analysis.Semantic proximity Read ↗

Apolipoprotein B and a second major gene locus contribute to phenotypic variation of spontaneous hypercholesterolemia in pigs.Semantic proximity Read ↗

Identification of a novel Arg-->Cys mutation in the LDL receptor that contributes to spontaneous hypercholesterolemia in pigs.Semantic proximity Read ↗

Low density lipoprotein heterogeneity in spontaneously hypercholesterolemic pigs.Semantic proximity Read ↗

Concentrations and compositions of plasma lipoprotein subfractions of Lpb5-Lpu1 homozygous and heterozygous swine with hypercholesterolemia.Semantic proximity Read ↗

Overproduction of a buoyant low density lipoprotein subspecies in spontaneously hypercholesterolemic mutant pigs.Semantic proximity Read ↗

Bi-PASA genotyping of a new polymorphism in the APOB gene shows no evidence for an association with fatness in pigs.Semantic proximity Read ↗

Identification of new apolipoprotein B epitopes and haplotypes and their distribution in swine populations.Semantic proximity Read ↗

Two new immunogenetic polymorphisms of the apoB gene and their effect on serum lipid levels and responses to changes in dietary fat intake.Semantic proximity Read ↗

Porcine von Willebrand disease and atherosclerosis. Influence of polymorphism in apolipoprotein B100 genotype.Semantic proximity Read ↗

Familial hypercholesterolemia associated with coronary atherosclerosis in swine bearing different alleles for apolipoprotein B.Semantic proximity Read ↗

Identification of apolipoprotein B100 polymorphisms that affect low-density lipoprotein metabolism: description of a new approach involving monoclonal antibodies and dynamic light scattering.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.