Article
Familial hypercholesterolemia associated with coronary atherosclerosis in swine bearing different alleles for apolipoprotein B.
Annals of the New York Academy of Sciences - 17 Jan 1995
Prescott M F, Hasler-Rapacz J, von Linden-Reed J, Rapacz J
Abstract excerpt
The development of advanced coronary atherosclerosis was studied in the FHC swine. This model exhibits spontaneous elevations in plasma cholesterol, LDL, and apo B while fed a low-cholesterol, low-fat diet. Hypercholesterolemic animals bearing the apo B genotypes Lpb2/3, 3/3, 3/5, 5/5 and 3/8 dev...
Topics
- Age Factors
- Alleles
- Animals
- Apolipoproteins B
- Arteriosclerosis
- Coronary Disease
- Female
- Hyperlipoproteinemia Type II
- Male
- Swine
- Swine Diseases