Article
Experimental reinfection of BALB/c mice with different recombinant type I/III strains of Toxoplasma gondii: involvement of IFN-gamma and IL-10.
Memorias do Instituto Oswaldo Cruz - 1 Mar 2009
Brandão Geane Peroni, Melo Maria Norma, Gazzinelli Ricardo Tostes, Caetano Braulia Costa, Ferreira Adriana Melo, Silva Letícia Azevedo, Vitor Ricardo Wagner Almeida
Abstract excerpt
To assess reinfection of BALB/c mice with different Toxoplasma gondii strains, the animals were prime infected with the non-virulent D8 strain and challenged with virulent recombinant strains. Thirty days after challenge, brain cysts were obtained from surviving BALB/c mice and inoculated in Swiss mice to obtain tachyzoites for DNA extraction and PCR-RFLP analysis to distinguish the different T. gondii strains...
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