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Article

IFN-γ Plays a Unique Role in Protection against Low Virulent Trypanosoma cruzi Strain

3 Apr 2012

Abstract excerpt

BACKGROUND: T. cruzi strains have been divided into six discrete typing units (DTUs) according to their genetic background. These groups are designated T. cruzi I to VI. In this context, amastigotes from G strain (T. cruzi I) are highly infective in vitro and show no parasitemia in vivo. Here we aimed to understand why amastigotes from G strain are highly infective in vitro and do not contribute for a patent in...

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PMID: 22509418
DOI: 10.1371/journal.pntd.0001598

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