Article
Induction of a secondary body axis in Xenopus by antibodies to beta-catenin.
The Journal of cell biology - 1 Oct 1993
McCrea P D, Brieher W M, Gumbiner B M
Abstract excerpt
We have obtained evidence that a known intracellular component of the cadherin cell-cell adhesion machinery, beta-catenin, contributes to the development of the body axis in the frog Xenopus laevis. Vertebrate beta-catenin is homologous to the Drosophila segment polarity gene product armadillo, a...
Topics
- Animals
- Antibody Specificity
- Cadherins
- Cell Adhesion
- Cell Division
- Cytoskeletal Proteins
- Embryo, Mammalian
- Embryo, Nonmammalian
- Embryonic and Fetal Development
- Female
- Gene Expression
- Growth Substances
- Humans
- Immunoglobulin Fab Fragments
- Microinjections
- Phenotype
- Trans-Activators
- Xenopus Proteins