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Article

A tetranucleotide repeat mouse minisatellite displaying substantial somatic instability during early preimplantation development.

Genomics - 1 Jul 1993

Gibbs M, Collick A, Kelly R G, Jeffreys A J

Abstract excerpt

The highly variable mouse minisatellite Hm-2 is located on chromosome 9 and consists of GGCA tetranucleotide repeats with alleles containing up to 5000 repeat units. This locus is unstable with a germline mutation rate to new length alleles of at least 3.6% per gamete. Hm-2 also shows substantial somatic instability, producing mutational mosaicism detectable in 20% of adult mice. Analysis of allele dosage in mice...

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Source

Identifiers

PMID: 8406443
DOI: 10.1006/geno.1993.1292

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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