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Article

Genetic analysis of mouse embryonic stem cells bearing Msh3 and Msh2 single and compound mutations.

Molecular and cellular biology - 1 Jan 2000

Abuin A, Zhang H, Bradley A

Abstract excerpt

We have previously described the use of homologous recombination and CRE-loxP-mediated marker recycling to generate mouse embryonic stem (ES) cell lines homozygous for mutations at the Msh3, Msh2, and both Msh3 and Msh2 loci (2). In this study, we describe the analysis of these ES cells with respect to processes known to be affected by DNA mismatch repair. ES cells homozygous for the Msh2 mutation displayed...

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Identifiers

PMID: 10594017
DOI: 10.1128/MCB.20.1.149-157.2000
PMCID: PMC85070

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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