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Article

Charged amino acids required for signal transduction by the m3 muscarinic acetylcholine receptor.

The EMBO journal - 1 Oct 1993

Kunkel M T, Peralta E G

Abstract excerpt

The five muscarinic acetylcholine receptor (mAChR) subtypes, termed m1-m5, transduce agonist signals across the plasma membrane by activating guanine nucleotide binding (G) proteins. The large cytoplasmic domain joining the fifth and sixth transmembrane segments of mAChRs plays a critical role in controlling the specificity of G protein coupling. In this study, we determined which sequences within this domain are...

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Identifiers

PMID: 8404851
DOI: 10.1002/j.1460-2075.1993.tb06059.x
PMCID: PMC413664

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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