Article
Evaluation of the primary effect of brefeldin A treatment upon herpes simplex virus assembly.
The Journal of general virology - 1 Jul 2001
Dasgupta Anindya, Wilson Duncan W
Abstract excerpt
Addition of the drug brefeldin A (BFA) to cells infected by herpes simplex virus (HSV) type 1 is known to result in a complex pattern of defects in particle assembly. BFA-treated, infected cells accumulate perinuclear enveloped virions and non-enveloped ("naked") cytoplasmic capsids, and it has been difficult to interpret these data in terms of the assembly pathway of HSV and the known effects of BFA on the...
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