Article
Binding to sialic acids is not an essential step for the entry of animal rotaviruses to epithelial cells in culture.
Journal of virology - 1 Sept 1993
Méndez E, Arias C F, López S
Abstract excerpt
The infection of target cells by animal rotaviruses requires the presence of sialic acids on the cell surface. Treatment of the cells with neuraminidases or incubation of the viruses with some sialoglycoproteins, such as glycophorin A, greatly reduces virus binding, with the consequent reduction of viral infectivity. In this work, we report the isolation of animal rotavirus variants whose infectivity is no longer...
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