Article
Initial interaction of rotavirus strains with N-acetylneuraminic (sialic) acid residues on the cell surface correlates with VP4 genotype, not species of origin.
Journal of virology - 1 Apr 2002
Ciarlet Max, Ludert Juan E, Iturriza-Gómara Miren, Liprandi Ferdinando, Gray James J, Desselberger Ulrich, Estes Mary K
Abstract excerpt
We examined 41 human and animal rotavirus strains representative of all known P genotypes for their dependency on cellular N-acetylneuraminic (sialic) acid (SA) residues for infectivity. Our results showed that all rotaviruses studied, whether of animal or human origin, belonging to P genotypes [...
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