Article
The sialic acid binding activity of the S protein facilitates infection by porcine transmissible gastroenteritis coronavirus.
Virology journal - 12 Sept 2011
Schwegmann-Wessels Christel, Bauer Sandra, Winter Christine, Enjuanes Luis, Laude Hubert, Herrler Georg
Abstract excerpt
BACKGROUND: Transmissible gastroenteritis virus (TGEV) has a sialic acid binding activity that is believed to be important for enteropathogenicity, but that has so far appeared to be dispensable for infection of cultured cells. The aims of this study were to determine the effect of sialic acid binding for the infection of cultured cells under unfavorable conditions, and comparison of TGEV strains and mutants, as...
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