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Article

High-resolution molecular and antigen structure of the VP8* core of a sialic acid-independent human rotavirus strain.

Journal of virology - 1 Feb 2006

Monnier Nilah, Higo-Moriguchi Kyoko, Sun Zhen-Yu J, Prasad B V Venkataram, Taniguchi Koki, Dormitzer Philip R

Abstract excerpt

The most intensively studied rotavirus strains initially attach to cells when the "heads" of their protruding spikes bind cell surface sialic acid. Rotavirus strains that cause disease in humans do not bind this ligand. The structure of the sialic acid binding head (the VP8* core) from the simian rotavirus strain RRV has been reported, and neutralization epitopes have been mapped onto its surface. We report here...

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Source

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Identifiers

PMID: 16415027
DOI: 10.1128/JVI.80.3.1513-1523.2006
PMCID: PMC1346936

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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