Article
A novel approach to clonality analysis. Alterations in genomic methylation of Epstein-Barr virus transformed lymphocytes.
Pathology, research and practice - 1 Apr 1993
Goldfarb A N, Litz C E
Abstract excerpt
We have studied eight different Epstein-Barr virus transformed cell lines (EBV-LCL) with respect to genomic methylation at a single locus, M-bcr (the major breakpoint cluster region of chronic myelogenous leukemia). Restriction digests with the methylation sensitive enzyme, Hpall, illustrated marked differences in M-bcr methylation patterns between the various cell lines. Some of the cell lines displayed...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
