Article
Augmented expression of cytosolic phospholipase A2 during phenotypic transformation of cultured type II pneumocytes.
The American journal of physiology - 1 Feb 1994
Peters-Golden M, Feyssa A
Abstract excerpt
Over time in culture, rat type II alveolar epithelial cells (AEC) demonstrate increased levels of unesterified arachidonic acid (AA) and increased prostanoid synthesis, while assuming certain morphological and biochemical characteristics of the type I cell phenotype. The objective of this study was to elucidate the enzymatic mechanism(s) responsible for increased AA accumulation in this model. Cells were examined...
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