Article

Pivotal role of the B7:CD28 pathway in transplantation tolerance and tumor immunity

1994-11-15

Abstract excerpt

Abstract The above story illustrates the translation of basic scientific discoveries to the clinic. In vitro and preclinical in vivo experimentation suggests that modulation of the B7:CD28 pathway will result in either amplification or suppression of the immune response. Considering the frequency with which diseases characterized by either inadequate or dysregulated immune function present to the practicing hemato...

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Identifiers and source

Literature Corpus work: 15670817-04f5-53fa-80ef-32c607524dff
DOI: 10.1182/blood.v84.10.3261.3261

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