Plasma cholinesterase activity and duration of action of mivacurium in phenotypically normal patients.

doi:10.1034/j.1399-6576.2002.460608.x

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Article

Plasma cholinesterase activity and duration of action of mivacurium in phenotypically normal patients.

Acta anaesthesiologica Scandinavica - 1 Jul 2002

ØStergaard Doris, Ibsen M, Skovgaard L, Viby-Mogensen J

Abstract excerpt

BACKGROUND: The short duration of action of mivacurium is due to its rapid hydrolysis by plasma cholinesterase (pChe). In patients with normal phenotype, low pChe activity because of, for instance, disease or intake of drugs may prolong the duration of action of mivacurium. The purpose of this study was to evaluate the relationship between pChe activity and the duration of action of mivacurium 0.2 mg/kg in...

Topics

Adult
Aged
Aged, 80 and over
Cholinesterases
Electric Stimulation
Female
Humans
Isoquinolines
Male
Middle Aged
Mivacurium
Neuromuscular Nondepolarizing Agents
Phenotype
Reaction Time
Reference Values
Time Factors

Source

Open in PubMed

Identifiers

PMID: 12059891
DOI: 10.1034/j.1399-6576.2002.460608.x

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