Article
Establishment of a novel cell line with T-lineage phenotype (HPB-MLp-W) from a non-Hodgkin's lymphoma patient.
Leukemia research - 1 Jan 1991
Morikawa S, Morikawa K, Hara J, Nagasaki M, Nakano A, Oseko F
Abstract excerpt
We report the characterization of a novel human T-cell line, HPB-MLp-W, which was established from blastic cells of a lymph node specimen from a patient with non-Hodgkin's lymphoma. They demonstrated the T-cell association antigens, CD2 and CD4, but no CD3, CD8, CD1, CD5, CD7 nor T-cell antigen receptor on their cell surfaces. They were also positive for Ia and Ki-1 antigen, and negative for CD25 (Tac-1). The...
Topics
- Antigens, CD
- Biopsy
- Cell Line
- Chromosome Banding
- Culture Techniques
- Female
- Gene Rearrangement, T-Lymphocyte
- Humans
- Karyotyping
- Lymph Nodes
- Lymphoma, Non-Hodgkin