Article
Establishment of an IL-2-dependent cell line derived from 'nasal-type' NK/T-cell lymphoma of CD2+, sCD3-, CD3epsilon+, CD56+ phenotype and associated with the Epstein-Barr virus.
British journal of haematology - 1 Dec 1998
Kagami Y, Nakamura S, Suzuki R, Iida S, Yatabe Y, Okada Y, Kobayashi T, Tsurumi T, Seto M, Ogura M, Taguchi O, Morishima Y
Abstract excerpt
A novel interleukin-2 (IL-2)-dependent cell line, HANK1, was established from a patient with CD56+ NK/T-cell lymphoma arising in the retroperitoneum. Morphologically, HANK1 is a pleomorphic large cell line with irregular nuclei, which contains azurophilic granules in the cytoplasm. Immunophenotyp...
Topics
- Blotting, Southern
- Blotting, Western
- CD2 Antigens
- CD3 Complex
- CD56 Antigen
- Cell Division
- Chromosome Aberrations
- Fatal Outcome
- Female
- Herpesvirus 4, Human
- Humans
- Immunohistochemistry
- Interleukin-2
- Killer Cells, Natural