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Article

Detection of 12 germ-line mutations in the adenomatous polyposis coli gene by polymerase chain reaction.

Gastroenterology - 1 Apr 1993

Ando H, Miyoshi Y, Nagase H, Baba S, Nakamura Y

Abstract excerpt

BACKGROUND: The adenomatous polyposis coli (APC) gene at chromosome 5q21 that is responsible for familial adenomatous polyposis (FAP) was recently isolated, and germ-line mutations in a substantial number of FAP families were characterized. Based on this information, the authors attempted to develop a presymptomatic diagnosis test for members of families that carry FAP. METHODS: A rapid screening procedure using...

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Source

Identifiers

PMID: 8385047
DOI: 10.1016/0016-5085(93)90265-e

Genes

FAP
APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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