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Article

Detecting mutations in the APC gene in familial adenomatous polyposis (FAP).

Current protocols in human genetics - 1 Aug 2006

Hegde Madhuri R, Roa Benjamin B

Abstract excerpt

Hereditary forms of colorectal cancer (CRC) account for up to 5% of total cases. Familial adenomatous polyposis (FAP) is an autosomal dominant condition affecting nearly 1 in 5000 people and accounts for only about 1% of all CRCs. It is characterized by the progressive development of hundreds to thousands of adenomatous colon polyps. The gene associated with FAP (APC) contains 15 exons in the coding region. A...

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Source

Identifiers

PMID: 18428386
DOI: 10.1002/0471142905.hg1008s50

Genes

APC
FAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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