Presymptomatic diagnosis of familial adenomatous polyposis coli.

doi:10.1007/BF02054415

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Article

Presymptomatic diagnosis of familial adenomatous polyposis coli.

Diseases of the colon and rectum - 1 Jul 1994

Park J G, Han H J, Kang M S, Nakamura Y

Abstract excerpt

UNLABELLED: Familial adenomatous polyposis (FAP), an autosomal dominant inherited disease, confers a high risk of colon cancer, and recently the gene responsible for FAP, termed adenomatous polyposis coli (APC) gene, was identified and fully characterized. PURPOSE: For the presymptomatic diagnosi...

Topics

Adenine Nucleotides
Adenomatous Polyposis Coli
Alleles
Base Sequence
Cytosine Nucleotides
Deoxyribonucleases, Type II Site-Specific
Female
Genes, APC
Genetic Linkage
Genetic Markers
Genotype
Haplotypes
Humans
Male
Molecular Sequence Data
Mutation
Pedigree
Phenotype

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