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Article

Novel mutations of the APC gene in familial adenomatous polyposis in Greek patients.

Cancer genetics and cytogenetics - 1 Feb 2003

Mihalatos M, Danielides I, Belogianni J, Harokopos E, Papadopoulou E, Kalimanis G, Tsiava M, Triantafillidis J K, Kosmidis P A, Fountzilas G, Basdanis G, Agnantis N J, Yannoukakos D, Nasioulas G

Abstract excerpt

Familial adenomatous polyposis (FAP), a premalignant clinical entity inherited as an autosomal dominant trait, is characterized by the development thousands of adenomatous polyps of the colorectum during the 2nd and 3rd decade of life. Approximately 80% of patients with FAP harbor truncating germline mutations in the adenomatous polyposis coli (APC) tumor suppressor gene. We tested 24 members of six Greek...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12581900
DOI: 10.1016/s0165-4608(02)00723-9

Genes

APC
FAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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