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Article

Spatial relationship of the Fis binding sites for Hin recombinational enhancer activity.

Nature - 1 Jan 2000

Johnson R C, Glasgow A C, Simon M I

Abstract excerpt

Site-specific recombination reactions involve the joining or rearrangement of discrete DNA segments in a highly precise manner. A site-specific DNA inversion regulates the expression of flagellin genes in Salmonella by switching the orientation of a promoter. Analysis of the reaction has shown that, in addition to DNA sequences at the two boundaries of the 1-kilobase invertible segment where strand exchange...

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PMID: 2821402
DOI: 10.1038/329462a0

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Spatial relationship of the Fis binding sites for Hin recombinational enhancer activity.PMID 2821402Read ↗

In vivo identification of intermediate stages of the DNA inversion reaction catalyzed by the Salmonella Hin recombinase.Semantic proximity Read ↗

Stimulation of DNA inversion by FIS: evidence for enhancer-independent contacts with the Gin-gix complex.Semantic proximity Read ↗

Mechanical constraints on Hin subunit rotation imposed by the Fis/enhancer system and DNA supercoiling during site-specific recombination.Semantic proximity Read ↗

Intrasubunit and intersubunit interactions controlling assembly of active synaptic complexes during Hin-catalyzed DNA recombination.Semantic proximity Read ↗

Analysis of strand exchange and DNA binding of enhancer-independent Gin recombinase mutants.Semantic proximity Read ↗

In vivo assay of protein-protein interactions in Hin-mediated DNA inversion.Semantic proximity Read ↗

Sequence, regulation, and functions of fis in Salmonella typhimurium.Semantic proximity Read ↗

The Hin dimer interface is critical for Fis-mediated activation of the catalytic steps of site-specific DNA inversion.Semantic proximity Read ↗

DNA binding and bending are necessary but not sufficient for Fis-dependent activation of rrnB P1.Semantic proximity Read ↗

Replication enhancer-independent mutation increases the co-operativity with which an initiator protein binds its origin.Semantic proximity Read ↗

Adjacent DNA sequences modulate Sox9 transcriptional activation at paired Sox sites in three chondrocyte-specific enhancer elements.Semantic proximity Read ↗

Two DNA invertases contribute to flagellar phase variation in Salmonella enterica serovar Typhimurium strain LT2.Semantic proximity Read ↗

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