Article
Induction of a low voltage-activated, fast-inactivating Ca2+ channel in cultured bone marrow stromal cells by dexamethasone.
Calcified tissue international - 1 Feb 1994
Publicover S J, Thomas G P, el Haj A J
Abstract excerpt
The production of biochemical markers associated with the osteoblastic phenotype, and accompanying changes in the expression of voltage-operated Ca2+ channels, have been examined in rat bone marrow stromal cell cultures treated with dexamethasone (10(-8) M). Whole cell clamp analysis of voltage-operated Ca2+ channels in control cultures (using Ba2+ as the charge carrier) revealed primarily a high...
Topics
- 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester
- Alkaline Phosphatase
- Animals
- Bone Marrow
- Bone Marrow Cells
- Calcium Channels
- Cells, Cultured
- Collagen
- Dexamethasone
- Electric Stimulation
