Article
Binding of bovine papillomavirus E1 to the origin is not sufficient for DNA replication.
Virology - 1 Mar 1993
Spalholz B A, McBride A A, Sarafi T, Quintero J
Abstract excerpt
Replication of the bovine papillomavirus (BPV-1) DNA requires both the viral E1 and E2 gene products. The minimal origin of replication, which resides in a 60-basepair fragment centered on the unique HpaI site of the BPV-1 genome, can be bound by the E1 protein and is flanked by E2 binding sites....
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Binding Sites
- Bovine papillomavirus 1
- Cell Line
- DNA Replication
- DNA-Binding Proteins
- Gene Expression Regulation, Viral
- Mice
- Molecular Sequence Data
- Mutation
- Protein Binding
- Transformation, Genetic
- Viral Proteins
- Virus Replication