Article
The bovine papilloma virus E1 protein has ATPase activity essential to viral DNA replication and efficient transformation in cells.
Virology - 1 Oct 1994
MacPherson P, Thorner L, Parker L M, Botchan M
Abstract excerpt
The bovine papilloma virus (BPV) E1 protein essential to viral DNA replication has recently been shown to associate via direct protein-DNA interactions with the viral origin of replication and to be an ATP-dependent helicase. We show here that in accordance with the latter function, the E1 gene product has intrinsic ATPase activity. Mutations placed throughout the nucleotide binding consensus element abolish the...
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