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Article

Glycoprotein gp50-negative pseudorabies virus: a novel approach toward a nonspreading live herpesvirus vaccine.

Journal of virology - 1 Mar 1993

Heffner S, Kovács F, Klupp B G, Mettenleiter T C

Abstract excerpt

Essential herpesvirus glycoproteins are involved in membrane fusion processes during infection, e.g., viral penetration and direct cell-to-cell transmission. We previously showed that the gD-homologous glycoprotein gp50 of pseudorabies virus (PrV) is essential for virus entry into target cells but proved to be dispensable for direct viral cell-to-cell spread in cell culture (I. Rauh and T. C. Mettenleiter, J....

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Source

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Identifiers

PMID: 8382308
DOI: 10.1128/JVI.67.3.1529-1537.1993
PMCID: PMC237523

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Glycoprotein gp50-negative pseudorabies virus: a novel approach toward a nonspreading live herpesvirus vaccine.PMID 8382308Read ↗

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