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Article

Bovine leukemia virus, an animal model for the study of intrastrain variability.

Journal of virology - 1 Feb 1993

Willems L, Thienpont E, Kerkhofs P, Burny A, Mammerickx M, Kettmann R

Abstract excerpt

Intradermal injection of a cloned bovine leukemia virus (BLV) provirus (pV344) into sheep allowed direct evaluation of intrastrain variability. A sheep was injected with pV344 DNA mixed with DEAE-dextran and became persistently infected with BLV strain 344. After 18 months, DNA was extracted from peripheral blood leukocytes from a single 0.5-ml blood sample. The long terminal repeat (LTR) and the env gene were...

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Identifiers

PMID: 8380455
DOI: 10.1128/JVI.67.2.1086-1089.1993
PMCID: PMC237465

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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