Article
Mutation of a Single Envelope N-Linked Glycosylation Site Enhances the Pathogenicity of Bovine Leukemia Virus.
Journal of virology - 1 Sept 2015
de Brogniez Alix, Bouzar Amel Baya, Jacques Jean-Rock, Cosse Jean-Philippe, Gillet Nicolas, Callebaut Isabelle, Reichert Michal, Willems Luc
Abstract excerpt
UNLABELLED: Viruses have coevolved with their host to ensure efficient replication and transmission without inducing excessive pathogenicity that would indirectly impair their persistence. This is exemplified by the bovine leukemia virus (BLV) system in which lymphoproliferative disorders develop in ruminants after latency periods of several years. In principle, the equilibrium reached between the virus and its...
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