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Article

Tumour necrosis factor-alpha can modulate the phenotype of aortic smooth muscle cells.

Scandinavian journal of clinical and laboratory investigation - 1 Jul 1993

Morisaki N, Xu Q P, Koshikawa T, Saito Y, Yoshida S, Ueda S

Abstract excerpt

In culture, rabbit aortic smooth muscle cells (SMC) from an atheroma differed phenotypically from SMC from normal media (M-SMC) in their growth rate, secretion of SMC-derived growth factor (SDGF), and metabolism of acetylated low density lipoproteins (a-LDL). The factor responsible for this in vivo phenotypic change of SMC was investigated in vitro. After preincubation of M-SMC with 0.1-10 U ml-1 of tumour...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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PMID: 8378737
DOI: 10.3109/00365519309086626

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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