Article
Phenotype related changes of intimal smooth muscle cells from human aorta in primary culture.
Atherosclerosis - 1 Oct 1992
Babaev V R, Antonov A S, Domogatsky S P, Kazantseva I A
Abstract excerpt
To study the functional characteristics of smooth muscle cell (SMC) phenotypes, we have investigated myosin expression, cell proliferation, collagen production and low-density lipoprotein (LDL) receptor activity in intimal SMCs of normal human aorta during their growth in primary culture. By staining with rabbit antibodies to smooth muscle myosin (ASMM) 3 cell types could be distinguished in culture:...
Topics
- Adult
- Aged
- Aorta, Thoracic
- Autoradiography
- Cell Division
- Collagen
- Culture Techniques
- DNA
- Fluorescent Antibody Technique
- Humans
- Immunohistochemistry
- Male
