Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Collagen synthesis by cultured rabbit aortic smooth-muscle cells. Alteration with phenotype.

The Biochemical journal - 15 Jan 1990

Ang A H, Tachas G, Campbell J H, Bateman J F, Campbell G R

Abstract excerpt

Enzymically isolated rabbit aortic smooth-muscle cells (SMC) in the first few days of primary culture express a 'contractile phenotype', but with time these cells modulate to a 'synthetic phenotype'. Synthetic-state SMC are able to proliferate, and, provided that they undergo fewer than 5 cumulative population doublings, return to the contractile phenotype after reaching confluency [Campbell, Kocher, Skalli,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Division
Share to Cells, Cultured
Share to Collagen

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Kinetics

Share to Nucleic Acid Hybridization

Share to Phenotype

Share to Protein Biosynthesis

Share to RNA, Messenger

Source

Open in PubMed Open full text

Identifiers

PMID: 1689147
DOI: 10.1042/bj2650461
PMCID: PMC1136907

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Collagen synthesis by cultured rabbit aortic smooth-muscle cells. Alteration with phenotype.PMID 1689147Read ↗

Collagen synthesis by cultured arterial smooth muscle cells during spontaneous phenotypic modulation.Semantic proximity Read ↗

Type I collagen promotes modulation of cultured rabbit arterial smooth muscle cells from a contractile to a synthetic phenotype.Semantic proximity Read ↗

Lipid biosynthesis in cultured arterial smooth muscle cells is related to their phenotype.Semantic proximity Read ↗

Retardation of phenotypic transition of rabbit arterial smooth muscle cells in three-dimensional primary culture.Semantic proximity Read ↗

Glycosaminoglycan synthesis by smooth muscle cells of differing phenotype and their response to endothelial cell conditioned medium.Semantic proximity Read ↗

Vascular smooth muscle cell phenotypic modulation in culture is associated with reorganisation of contractile and cytoskeletal proteins.Semantic proximity Read ↗

A role for rho in smooth muscle phenotypic regulation.Semantic proximity Read ↗

Competence growth factors evoke the phenotypic transition of arterial smooth muscle cells.Semantic proximity Read ↗

Fibronectin and the basement membrane components laminin and collagen type IV influence the phenotypic properties of subcultured rat aortic smooth muscle cells differently.Semantic proximity Read ↗

Expression of phenotype- and proliferation-related genes in rat aortic smooth muscle cells in primary culture.Semantic proximity Read ↗

Rho expression and activation in vascular smooth muscle cells.Semantic proximity Read ↗

Coordinate regulation of matrix metalloproteinase-1 and tissue inhibitor of metalloproteinase-1 expression in human vascular smooth muscle cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.