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Article

A method for selection of mutations at the tdk locus in Escherichia coli.

Journal of bacteriology - 1 Sept 1993

Summers W C, Raksin P

Abstract excerpt

Mutants of Escherichia coli which are resistant to 5-fluorodeoxyuridine all have mutations which map at a single locus at 27.5 min on the genetic map of E. coli. Extracts prepared from each mutant were deficient in thymidine kinase activity measured in vitro. Simple selective conditions which allowed detection of one mutant in the presence of 10(7) wild-type bacteria were found. These results show that loss of...

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Identifiers

PMID: 8376351
DOI: 10.1128/jb.175.18.6049-6051.1993
PMCID: PMC206689

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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