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Article

Activated Notch4 Inhibits Angiogenesis: Role of β1-Integrin Activation

1 Apr 2002

Abstract excerpt

Notch4 is a member of the Notch family of transmembrane receptors that is expressed primarily on endothelial cells. Activation of Notch in various cell systems has been shown to regulate cell fate decisions. The sprouting of endothelial cells from microvessels, or angiogenesis, involves the modulation of the endothelial cell phenotype. Based on the function of other Notch family members and the expression pattern...

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Identifiers

PMID: 11909975
DOI: 10.1128/mcb.22.8.2830-2841.2002

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Source receipt: pubmed, retrieved 7 Sept 2026.

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