Article
The effect of deleterious mutations on neutral molecular variation.
Genetics - 1 Aug 1993
Charlesworth B, Morgan M T, Charlesworth D
Abstract excerpt
Selection against deleterious alleles maintained by mutation may cause a reduction in the amount of genetic variability at linked neutral sites. This is because a new neutral variant can only remain in a large population for a long period of time if it is maintained in gametes that are free of de...
Topics
- Animals
- Computer Simulation
- Drosophila melanogaster
- Genetic Variation
- Inbreeding
- Models, Genetic
- Mutation
- Recombination, Genetic
- Reproduction
- Selection, Genetic