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Article

Background selection 20 years on: the Wilhelmine E. Key 2012 invitational lecture.

The Journal of heredity - 1 Mar 2013

Charlesworth Brian

Abstract excerpt

The mutation process continually produces new deleterious variants at sites throughout the genome, which are then mostly eliminated by selection. This causes a reduction in variability at linked neutral or nearly neutral sites, as well as distortions of the genealogies of samples of alleles from a population. In regions of the genome where recombination is frequent, the effects of selection against deleterious...

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PMID: 23303522
DOI: 10.1093/jhered/ess136

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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