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Article

The effects of deleterious mutations on evolution at linked sites.

Genetics - 1 Jan 2012

Charlesworth Brian

Abstract excerpt

The process of evolution at a given site in the genome can be influenced by the action of selection at other sites, especially when these are closely linked to it. Such selection reduces the effective population size experienced by the site in question (the Hill-Robertson effect), reducing the level of variability and the efficacy of selection. In particular, deleterious variants are continually being produced by...

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Identifiers

PMID: 22219506
DOI: 10.1534/genetics.111.134288
PMCID: PMC3249359

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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