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Article

The Effect of Strong Purifying Selection on Genetic Diversity.

Genetics - 1 Aug 2018

Cvijović Ivana, Good Benjamin H, Desai Michael M

Abstract excerpt

Purifying selection reduces genetic diversity, both at sites under direct selection and at linked neutral sites. This process, known as background selection, is thought to play an important role in shaping genomic diversity in natural populations. Yet despite its importance, the effects of background selection are not fully understood. Previous theoretical analyses of this process have taken a backward-time...

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Identifiers

PMID: 29844134
DOI: 10.1534/genetics.118.301058
PMCID: PMC6063222

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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