The effect of recombination on background selection.

doi:10.1017/s0016672300033619

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Article

The effect of recombination on background selection.

Genetical research - 1 Apr 1996

Nordborg M, Charlesworth B, Charlesworth D

Abstract excerpt

An approximate equation is derived, which predicts the effect on variability at a neutral locus of background selection due to a set of partly linked deleterious mutations. Random mating, multiplicative fitnesses, and sufficiently large population size that the selected loci are in mutation/selec...

Topics

Animals
Chromosomes
Computer Simulation
Drosophila melanogaster
Genetic Linkage
Models, Genetic
Monte Carlo Method
Mutation
Recombination, Genetic
Selection, Genetic

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