Article
The effect of background selection against deleterious mutations on weakly selected, linked variants.
Genetical research - 1 Jun 1994
Charlesworth B
Abstract excerpt
This paper analyses the effects of selection against deleterious alleles maintained by mutation ('background selection') on rates of evolution and levels of genetic diversity at weakly selected, completely linked, loci. General formulae are derived for the expected rates of gene substitution and...
Topics
- Animals
- Biological Evolution
- Drosophila
- Female
- Genetic Variation
- Male
- Models, Genetic
- Mutation
- Selection, Genetic