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Article

The effects of deleterious mutations on linked, neutral variation in small populations.

Genetics - 1 Sept 1999

Pálsson S, Pamilo P

Abstract excerpt

The effects of recessive, deleterious mutations on genetic variation at linked neutral loci can be heterozygosity-decreasing because of reduced effective population sizes or heterozygosity-increasing because of associative overdominance. Here we examine the balance between these effects by simulating individual diploid genotypes in small panmictic populations. The haploid genome consists of one linkage group with...

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Identifiers

PMID: 10471727
DOI: 10.1093/genetics/153.1.475
PMCID: PMC1460752

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Source receipt: pubmed, retrieved 7 Sept 2026.

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