Article
Recombination walking: genetic selection of clones from pooled libraries of yeast artificial chromosomes by homologous recombination.
Proceedings of the National Academy of Sciences of the United States of America - 1 Sept 1993
Miller A M, Savinelli E A, Couture S M, Hannigan G M, Han Z, Selden R F, Treco D A
Abstract excerpt
Recombination walking is based on the genetic selection of specific human clones from a yeast artificial chromosome (YAC) library by homologous recombination. The desired clone is selected from a pooled (unordered) YAC library, eliminating labor-intensive steps typically used in organizing and maintaining ordered YAC libraries. Recombination walking represents an efficient approach to library screening and is...
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