Mutation in the plasmid pUB110 Rep protein affects termination of rolling circle replication.

doi:10.1128/jb.175.17.5611-5616.1993

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Article

Mutation in the plasmid pUB110 Rep protein affects termination of rolling circle replication.

Journal of bacteriology - 1 Sept 1993

Bidnenko V E, Gruss A, Ehrlich S D

Abstract excerpt

We isolated a mutant of plasmid pUB110 that has the following properties in Bacillus subtilis: (i) it is toxic for recA and add cells, particularly at elevated temperature; (ii) it has a copy number threefold higher than that of the parental plasmid, and the extra copies are present as multimers; and (iii) it can efficiently complement replication of a cmp- satellite plasmid, despite being cmp+. All these...

Topics

Amino Acid Sequence
Bacillus subtilis
Bacterial Proteins
Base Sequence
DNA Helicases
DNA Replication
DNA, Bacterial
DNA-Binding Proteins
Gene Deletion
Genetic Complementation Test
Molecular Sequence Data
Mutation
Plasmids
Trans-Activators

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Identifiers

PMID: 8366045
DOI: 10.1128/jb.175.17.5611-5616.1993
PMCID: PMC206618

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