Article
A rapid method for cloning mutagenic DNA repair genes: isolation of umu-complementing genes from multidrug resistance plasmids R391, R446b, and R471a.
Journal of bacteriology - 1 Sept 1993
Ho C, Kulaeva O I, Levine A S, Woodgate R
Abstract excerpt
Genetic and physiological experiments have demonstrated that the products of the umu-like operon are directly required for mutagenic DNA repair in enterobacteria. To date, five such operons have been cloned and studied at the molecular level. Given the apparent wide occurrence of these mutagenic...
Topics
- Cloning, Molecular
- DNA Repair
- DNA, Bacterial
- Drug Resistance, Microbial
- Escherichia coli
- Genes, Bacterial
- Genetic Complementation Test
- Mutagenesis
- Phenotype
- R Factors
- Restriction Mapping
- Ultraviolet Rays