Article
The Pathology of Aging 129S6/SvEvTac Mice.
Veterinary pathology - 1 Mar 2016
Radaelli E, Castiglioni V, Recordati C, Gobbi A, Capillo M, Invernizzi A, Scanziani E, Marchesi F
Abstract excerpt
The 129 mouse strain is commonly used for the generation of genetically engineered mice. Genetic drift or accidental contamination during outcrossing has resulted in several 129 substrains. Comprehensive data on spontaneous age-related pathology exist for the 129S4/SvJae substrain, whereas only limited information is available for other 129 substrains. This longitudinal aging study describes the life span and...
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